Synthesis of size-tunable polymeric nanoparticles enabled by 3D hydrodynamic flow focusing in single-layer microchannels.

نویسندگان

  • Minsoung Rhee
  • Pedro M Valencia
  • Maria I Rodriguez
  • Robert Langer
  • Omid C Farokhzad
  • Rohit Karnik
چکیده

Recently, polymeric nanoparticles (NPs) have attracted enormous attention as targeted drug delivery vehicles.[1-4] Especially, biodegradable and biocompatible polymeric NPs comprised of poly(lactide-co-glycolide)-b-polyethyleneglycol (PLGA-PEG) block copolymers exhibit optimal physicochemical characteristics such as the ability to incorporate various targeting agents, enhanced immune evasion, controlled drug release, and

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عنوان ژورنال:
  • Advanced materials

دوره 23 12  شماره 

صفحات  -

تاریخ انتشار 2011